# Germline Data Filtering

 To filter with germline data, use the “+ Add Filter” button in the Cohort Banner. 

## **These filters allow for:**

* Assessing impact of ingested variants in cohorts
* Note: only non-ref variants are represented in the genomic data
* Building Cohorts based on Variants
* Develop basket studies based on your population
* Exploratory Data Analysis before GWAS
* Ask questions about co-occurrence with other mutations

## **You Can Filter By:**

* Gene Symbol or region
* Variant effect
* Variant type
* Variant ID

## Adding Germline Filters

1. Add in your dataset
2. Select "+ Add Filter"

<figure><img src="/files/TPFit1kScTRY3RAtTQwe" alt=""><figcaption></figcaption></figure>

3. Select Assays and then under Genome Sequencing, select “Genes/ Effects”&#x20;

<figure><img src="/files/hWb5CzbdqamnggoHlgJm" alt=""><figcaption></figcaption></figure>

4. Then, select the genes/ impact/ variants that you want. Please note, the filtering for the Genes/ Genomic regions is by Gene Symbol or Genomic range.

<figure><img src="/files/dizPIyuBMjmZVlnEv2mJ" alt=""><figcaption></figcaption></figure>

## Supplemental Video: Germline Data Tab + Filtering

{% embed url="<https://youtu.be/F6djFOolyME>" %}


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