Germline Data Filtering

To filter with germline data, use the “+ Add Filter” button in the Cohort Banner.

These filters allow for:

• Assessing impact of ingested variants in cohorts

• Note: only non-ref variants are represented in the genomic data

• Building Cohorts based on Variants

• Develop basket studies based on your population

• Exploratory Data Analysis before GWAS

• Ask questions about co-occurrence with other mutations

You Can Filter By:

• Gene Symbol or region

• Variant effect

• Variant type

• Variant ID

Adding Germline Filters

1. Add in your dataset

2. Select "+ Add Filter"

1. Select Assays and then under Genome Sequencing, select “Genes/ Effects”

1. Then, select the genes/ impact/ variants that you want. Please note, the filtering for the Genes/ Genomic regions is by Gene Symbol or Genomic range.

Supplemental Video: Germline Data Tab + Filtering