# Germline Data Filtering

&#x20;To filter with germline data, use the “+ Add Filter” button in the Cohort Banner.&#x20;

## **These filters allow for:**

* Assessing impact of ingested variants in cohorts
* Note: only non-ref variants are represented in the genomic data
* Building Cohorts based on Variants
* Develop basket studies based on your population
* Exploratory Data Analysis before GWAS
* Ask questions about co-occurrence with other mutations

## **You Can Filter By:**

* Gene Symbol or region
* Variant effect
* Variant type
* Variant ID

## Adding Germline Filters

1. Add in your dataset
2. Select "+ Add Filter"

<figure><img src="https://1979569080-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FPtCOm9rXoRi4P9rh1ET8%2Fuploads%2FIYpvTHprCgRe67jlDFat%2Funknown.png?alt=media&#x26;token=808abc8c-8935-405b-bd50-e88201e8d165" alt=""><figcaption></figcaption></figure>

3. Select Assays and then under Genome Sequencing, select “Genes/ Effects”&#x20;

<figure><img src="https://1979569080-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FPtCOm9rXoRi4P9rh1ET8%2Fuploads%2F877utQViO2POpS8sNN0A%2Funknown.png?alt=media&#x26;token=1da823cb-a85d-46db-8ead-aa3391708eae" alt=""><figcaption></figcaption></figure>

4. Then, select the genes/ impact/ variants that you want. Please note, the filtering for the Genes/ Genomic regions is by Gene Symbol or Genomic range.

<figure><img src="https://1979569080-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FPtCOm9rXoRi4P9rh1ET8%2Fuploads%2FoywdywzTF86bCvy3oLri%2Funknown.png?alt=media&#x26;token=3cc0b3ee-ea14-4481-8b9a-0aeb54a379ff" alt=""><figcaption></figcaption></figure>

## Supplemental Video: Germline Data Tab + Filtering

{% embed url="<https://youtu.be/F6djFOolyME>" %}
